| 09.05.2021 16:40 | Čukarički | 0 : 2 | Partizan | |
| 09.05.2021 14:30 | TSC | 2 : 1 | Javor Matis | |
| 09.05.2021 14:30 | Spartak ŽK | 1 : 0 | Inđija | |
| 09.05.2021 14:30 | Mačva | 2 : 5 | Vojvodina | |
| 09.05.2021 14:30 | Radnički (N) | 2 : 2 | Rad | |
| 09.05.2021 18:45 | Crvena zvezda | 6 : 1 | Zlatibor | |
| 09.05.2021 14:30 | Metalac | 3 : 0 | OFK Bačka |
| 09.05.2021 17:00 | Dinamo | 1 : 0 | Zemun | |
| 09.05.2021 17:00 | Borac 1926 | 0 : 1 | Loznica | |
| 09.05.2021 17:00 | OFK Žarkovo | 0 : 3 | Kolubara | |
| 09.05.2021 17:00 | Radnički 1923 | 1 : 0 | Trayal | |
| 09.05.2021 17:00 | Kabel | 0 : 1 | Budućnost | |
| 09.05.2021 17:00 | Radnički (P) | 0 : 1 | GFK Jagodina | |
| 09.05.2021 17:00 | Radnički (SM) | 1 : 0 | Sloga (K) |
| 09.05.2021 16:30 | Borac | 0 : 1 | Zvijezda 09 |
| 09.05.2021 17:00 | Vojvodina 1928 | 0 : 1 | 1. Maj Ruma | |
| 09.05.2021 17:00 | Tisa | 0 : 2 | Sloboda |
| 09.05.2021 16:30 | Sušica | 1 : 0 | GFK Sloboda | |
| 09.05.2021 16:30 | Jošanica | 2 : 1 | Tutin | |
| 09.05.2021 16:30 | Budućnost (A) | 1 : 2 | Smederevo 1924 |
| 09.05.2021 16:30 | BASK | 1 : 4 | Teleoptik | |
| 09.05.2021 16:30 | Crvena zvezda | 1 : 2 | BSK Borča | |
| 09.05.2021 16:30 | BSK 1925 | 0 : 0 | Zvezdara | |
| 09.05.2021 16:30 | Sremčica | 0 : 1 | TEK Sloga | |
| 09.05.2021 16:30 | Leštane | 5 : 2 | Brodarac | |
| 09.05.2021 17:30 | Studentski grad | 1 : 0 | Sinđelić |
| 09.05.2021 17:00 | Radan | 0 : 1 | Vlasina | |
| 09.05.2021 17:00 | Timočanin | 2 : 1 | Rembas | |
| 09.05.2021 17:00 | Mladost | 2 : 0 | Župa | |
| 09.05.2021 17:00 | Kablovi | 0 : 9 | Car Konstantin |
| 09.05.2021 16:30 | Polet | 1 : 0 | Šumadija 1903 | |
| 09.05.2021 16:30 | Real | 3 : 0 | Mokra Gora | |
| 09.05.2021 11:00 | Proleter | 2 : 2 | Budućnost | |
| 09.05.2021 16:30 | Radnik | 2 : 0 | Novi Pazar 1928 | |
| 09.05.2021 16:30 | Vodojaža | 2 : 1 | Šumadija (T) | |
| 09.05.2021 16:30 | OFK Ras | 1 : 2 | Omladinac |
| 09.05.2021 16:30 | OFK Napredak | 2 : 3 | RSK | |
| 09.05.2021 16:30 | Pomoravlje | 0 : 0 | Rudar (S) | |
| 09.05.2021 16:30 | Sloboda | 3 : 0 | Petar Dobrnjac | |
| 09.05.2021 16:30 | Borac 1932 | 4 : 2 | VGSK | |
| 09.05.2021 16:30 | OFK Mihajlovac | 5 : 0 | Sloga (M) |
| 09.05.2021 16:30 | Sloboda (Č) | 1 : 2 | Parmenac | |
| 09.05.2021 16:30 | Jasen | 6 : 2 | Omladinac | |
| 09.05.2021 16:30 | Rampa | 1 : 3 | Polet (Lj) | |
| 09.05.2021 16:30 | Prijevor | 3 : 0 | Polimlje |
| 09.05.2021 16:30 | Spartak 1924 | 1 : 2 | Rubribreza | |
| 09.05.2021 16:30 | Sloga (B) | 4 : 1 | Mladost (P) | |
| 09.05.2021 16:30 | Mladost (Dr) | 1 : 2 | Vrelo Sport | |
| 09.05.2021 16:30 | Borac (L) | 2 : 0 | Ribnica | |
| 09.05.2021 16:30 | Zadrugar | 5 : 0 | Mladost (DD) | |
| 09.05.2021 16:30 | Radnički (K) | 0 : 2 | OFK Divci |
| 09.05.2021 17:00 | Hercegovac | 2 : 0 | Crvenka | |
| 09.05.2021 17:00 | Bačka (P) | 3 : 2 | Vojvodina (BG) | |
| 09.05.2021 17:00 | Mladost (T) | 7 : 0 | Radnički (S) | |
| 09.05.2021 17:00 | Mladost (BP) | 1 : 0 | Tavankut |
| 09.05.2021 17:00 | Omladinac FAM | 5 : 2 | Proleter | |
| 09.05.2021 17:00 | Radnički (K) | 2 : 4 | Budućnost | |
| 09.05.2021 17:00 | ŽAK | 1 : 3 | Crvena zvezda |
| 09.05.2021 10:00 | Index | 2 : 0 | Sremac Vojka | |
| 09.05.2021 17:00 | Jedinstvo | 2 : 0 | Podrinje | |
| 09.05.2021 17:00 | Borac | 1 : 0 | Cement | |
| 09.05.2021 17:00 | Hajduk | 3 : 4 | Sloboda | |
| 09.05.2021 17:00 | Budućnost | 0 : 1 | RFK Novi Sad 1921 | |
| 09.05.2021 17:00 | Jadran | 0 : 2 | Radnički |
| 09.05.2021 17:00 | Levač | 2 : 0 | OFK Lugomir | |
| 09.05.2021 17:00 | Sloga (M) | 3 : 0 | Moravac 2015 | |
| 09.05.2021 17:00 | Juhor | 1 : 3 | Morava 1918 | |
| 09.05.2021 17:00 | Kušiljevo | 5 : 0 | Temnić 1924 | |
| 09.05.2021 17:00 | Jastrebac | 3 : 1 | Blagotin | |
| 09.05.2021 17:00 | Jedinstvo (M) | 2 : 0 | Kopaonik |
| 09.05.2021 17:00 | Lužnica | 2 : 1 | Tanasko Rajić | |
| 09.05.2021 17:00 | Branik | 0 : 0 | Rajko Mitić | |
| 09.05.2021 17:00 | OFK 019 | 4 : 3 | BSK | |
| 09.05.2021 11:00 | Jedinstvo (P) | 3 : 1 | OFK Slatina |
| 09.05.2021 17:00 | Naša krila 1936 | 2 : 1 | Zemljoradnik | |
| 09.05.2021 17:00 | OFK Niš | 1 : 2 | Jedinstvo (GM) | |
| 09.05.2021 17:00 | Morava | 1 : 2 | Bukovik | |
| 09.05.2021 17:00 | OFK Brzi Brod | 4 : 2 | Rudar | |
| 09.05.2021 17:00 | Malošište | 2 : 3 | Delijski Vis |
| 09.05.2021 17:00 | Dobrič | 1 : 2 | Vranjska Banja | |
| 09.05.2021 17:00 | Svetlost | 1 : 2 | OFK Kosanica | |
| 09.05.2021 17:00 | Čekmin | 2 : 1 | Alakince | |
| 09.05.2021 17:00 | Jedinstvo (G) | 1 : 2 | Budućnost |
| 09.05.2021 10:00 | Torlak | 7 : 0 | Mladost (C) | |
| 09.05.2021 16:30 | Kosmaj | 2 : 3 | Prva iskra | |
| 09.05.2021 16:30 | Poštar Zvezdara | 1 : 0 | Milutinac | |
| 09.05.2021 16:30 | Srem | 3 : 1 | Dunav | |
| 09.05.2021 16:30 | Borac (L) | 3 : 1 | Šumadija | |
| 09.05.2021 16:30 | Turbina | 2 : 0 | Vrčin |
| 09.05.2021 17:00 | OFK Rtanj | 0 : 0 | Omladinac | |
| 09.05.2021 17:00 | Rudar (P) | 2 : 2 | Graničar | |
| 09.05.2021 17:00 | Šljivar | 0 : 2 | Trebič | |
| 09.05.2021 17:00 | Kosovo | 1 : 4 | Rtanj | |
| 09.05.2021 17:00 | Sloga | 3 : 1 | Osnić |
| 09.05.2021 17:00 | Sloga (D) | 3 : 1 | Mačkovac | |
| 09.05.2021 17:00 | Vinogradar | 2 : 1 | Gornji Stepoš | |
| 09.05.2021 17:00 | Mladost (DK) | 3 : 2 | Sloga (Ć) | |
| 09.05.2021 17:00 | 13. April | 1 : 1 | Donji Kopaonik | |
| 09.05.2021 17:00 | Mladost (T) | 1 : 1 | Kupci | |
| 09.05.2021 17:00 | Žabare | 2 : 0 | Trudbenik | |
| 09.05.2021 17:00 | Sebečevac | 2 : 2 | FUD |
| 09.05.2021 17:00 | Mitros | 3 : 0 | Rudar | |
| 09.05.2021 17:00 | PSK | 0 : 9 | Železničar | |
| 09.05.2021 17:00 | Borac (M) | 0 : 1 | Donji Srem 2015 | |
| 09.05.2021 17:00 | Hajduk (V) | 2 : 1 | BSK | |
| 09.05.2021 17:00 | Ljukovo | 2 : 0 | Napredak | |
| 09.05.2021 17:00 | Hajduk (B) | 1 : 1 | Sloga | |
| 09.05.2021 17:00 | Borac (K) | 0 : 2 | Radnički | |
| 09.05.2021 17:00 | LSK | 1 : 5 | Partizan |
| 09.05.2021 17:00 | Spartak 1911 | 1 : 2 | Jugoslavija | |
| 09.05.2021 17:00 | Partizan (G) | 0 : 4 | Banat (I) | |
| 09.05.2021 17:00 | Polet (Id) | 5 : 0 | Partizan (U) | |
| 09.05.2021 17:00 | Potporanj | 3 : 1 | Hajdučica | |
| 09.05.2021 17:00 | Sloga (BNS) | 3 : 0 | Crvena zvezda | |
| 09.05.2021 17:00 | Stari Tamiš | 10 : 0 | Radnički (B) | |
| 09.05.2021 17:00 | Budućnost (A) | 2 : 1 | Dolina |
| 09.05.2021 17:00 | Borac 46 | 1 : 2 | Budućnost (P) | |
| 09.05.2021 17:00 | Budućnost (G) | 3 : 1 | Zadrugar | |
| 09.05.2021 17:00 | Rusin | 0 : 0 | Stanišić 1920 | |
| 09.05.2021 17:00 | Omladinac | 1 : 3 | Radnički 1918 | |
| 09.05.2021 17:00 | Maglić | 1 : 1 | Tvrđava | |
| 09.05.2021 17:00 | Kulpin | 2 : 2 | Budućnost (M) | |
| 09.05.2021 17:00 | Slavija | 2 : 0 | Polet |
| 09.05.2021 17:00 | Eđšeg | 1 : 3 | Iskra | |
| 09.05.2021 17:00 | Preporod | 2 : 0 | AFK | |
| 09.05.2021 17:00 | Obilić | 3 : 3 | Senta | |
| 09.05.2021 17:00 | Budućnost | 1 : 6 | Đurđin |
| 09.05.2021 17:00 | Polet | 2 : 2 | Radnički 1911 | |
| 09.05.2021 17:00 | Tamiš | 2 : 2 | ASK | |
| 09.05.2021 17:00 | Borac | 2 : 1 | Vojvodina (B) | |
| 09.05.2021 17:00 | Vojvodina (NM) | 2 : 1 | Potisje | |
| 09.05.2021 17:00 | 2. Oktobar | 3 : 1 | Mladost (L) | |
| 09.05.2021 17:00 | Mladost (BD) | 2 : 2 | Crvena zvezda | |
| 09.05.2021 17:00 | OFK Klek | 0 : 2 | Rusanda |
| 09.05.2021 16:30 | Polet | 2 : 1 | Budućnost | |
| 09.05.2021 16:30 | Obilić | 1 : 1 | Pobeda | |
| 09.05.2021 16:30 | SASK | 3 : 2 | Sloga (M) | |
| 09.05.2021 16:30 | Železničar Kusadak | 9 : 0 | Podunavac | |
| 09.05.2021 16:30 | Bresje Superior | 0 : 2 | Mladost 1948 | |
| 09.05.2021 16:30 | Osipaonica | 2 : 1 | Crvena zvezda | |
| 09.05.2021 16:30 | Bačinac | 3 : 4 | Sloga (L) | |
| 09.05.2021 16:30 | Mladi borac | 4 : 0 | Mladi radnik 1940 |
| 09.05.2021 16:30 | Šumadinac 1913 | 1 : 2 | Borac (P) | |
| 09.05.2021 16:30 | Grizli ML | 6 : 1 | Jasenica (B) | |
| 09.05.2021 16:30 | Vinča | 3 : 4 | Trnava | |
| 09.05.2021 16:30 | Partizan (BB) | 3 : 2 | Omladinac | |
| 09.05.2021 16:30 | Šumadinac (S) | 2 : 0 | ŽSK | |
| 09.05.2021 16:30 | Sloga (Z) | 2 : 1 | Plaskovac | |
| 09.05.2021 16:30 | Lokomotiva | 5 : 2 | Marjan (K) |
| 09.05.2021 16:00 | 011 | 2 : 3 | Sinđelić 2012 | |
| 09.05.2021 16:30 | PKB Kovilovo | 1 : 2 | Šumadinac | |
| 09.05.2021 16:30 | Umka | 5 : 1 | Borac (P) | |
| 09.05.2021 16:30 | Heroj Polet | 2 : 0 | Postar 1930 | |
| 09.05.2021 16:30 | Posavac Tišma | 2 : 0 | Institut | |
| 09.05.2021 16:30 | Balkan Mirijevo | 1 : 2 | Hajduk | |
| 09.05.2021 16:30 | DIF | 0 : 1 | PKB (PS) |
| 09.05.2021 16:30 | Omladinac | 7 : 1 | Mladi borac | |
| 09.05.2021 16:30 | Jedinstvo | 1 : 4 | Strelac | |
| 09.05.2021 16:30 | Zvezda | 6 : 3 | Vranić | |
| 09.05.2021 16:30 | OFK Borac | 3 : 3 | Radnički | |
| 09.05.2021 16:30 | OFK Zabrežje | 3 : 0 | Polet | |
| 09.05.2021 16:30 | OFK Budućnost | 4 : 2 | Rojkovac |
| 09.05.2021 16:30 | SUF Dubona | 3 : 1 | Velika Krsna | |
| 09.05.2021 16:30 | Pudarci | 2 : 1 | Kaluđerica 1969 | |
| 09.05.2021 16:30 | Zaklopača | 0 : 2 | Rabrovac | |
| 09.05.2021 16:30 | Kosmajac | 1 : 2 | Ivanča | |
| 09.05.2021 16:30 | Boleč | 0 : 2 | Zuce 2019 | |
| 09.05.2021 16:30 | Šumadija 1962 | 3 : 8 | Dunavac |
| 09.05.2021 17:30 | Bačka (B) | 0 : 3 | Titel | |
| 09.05.2021 17:30 | Tatra | 2 : 0 | Hajduk | |
| 09.05.2021 17:30 | Bačka 1923 | 0 : 4 | TSK | |
| 09.05.2021 17:30 | Petrovaradin | 2 : 2 | Šajkaš 1908 | |
| 09.05.2021 17:30 | ŽSK | 0 : 2 | Slavija | |
| 09.05.2021 17:30 | Fruškogorac | 1 : 0 | OFK Sirig |
| 09.05.2021 17:00 | Nemetali | 2 : 1 | Radnički | |
| 09.05.2021 11:00 | Sloga | 0 : 1 | BSK | |
| 09.05.2021 17:00 | Polet | 5 : 1 | Ključ |
| 09.05.2021 16:30 | Pobeda 1926 | 2 : 5 | Maršić | |
| 09.05.2021 16:30 | Šumadinac KG | 2 : 0 | Srbija | |
| 09.05.2021 16:30 | Zastava | 2 : 1 | Slavija | |
| 09.05.2021 16:30 | Jedinstvo | 4 : 1 | 21. oktobar | |
| 09.05.2021 16:30 | Kutlovo | 3 : 0 | OFK Bagremar |
| 09.05.2021 17:00 | Morava | 1 : 3 | Mladost (L) | |
| 09.05.2021 17:00 | Omladinac | 2 : 1 | Čegar 1946 | |
| 09.05.2021 17:00 | Sloboda | 6 : 2 | Crvena zastava | |
| 09.05.2021 17:00 | Mladost (DK) | 0 : 3 | Čegar 2013 | |
| 09.05.2021 17:00 | Radnički 1936 | 0 : 3 | Palilulac | |
| 09.05.2021 17:00 | Vulkan 1963 | 7 : 1 | Planinac 1933 |
| 09.05.2021 16:30 | Vihor | 8 : 0 | Manastirica | |
| 09.05.2021 16:30 | Integral | 1 : 0 | Budućnost (V) | |
| 09.05.2021 16:30 | Mladost (B) | 2 : 1 | Železničar | |
| 09.05.2021 16:30 | Rudar (Kr) | 1 : 0 | Napredak Simićevo | |
| 09.05.2021 16:30 | Borac (K) | 2 : 1 | Rudar 2001 | |
| 09.05.2021 16:30 | Mlava (ML) | 1 : 5 | Obilić | |
| 09.05.2021 16:30 | Sirakovo | 2 : 3 | Sloga (L) |
| 09.05.2021 17:00 | Elid | 0 : 6 | Mladost | |
| 09.05.2021 17:00 | Pobeda | 1 : 2 | Moravac (ZT) | |
| 09.05.2021 17:00 | Jastrebac | 3 : 2 | Svrljig | |
| 09.05.2021 17:00 | Sloga | 0 : 3 | Taskovići | |
| 09.05.2021 11:00 | Palilula | 3 : 4 | Baličevac | |
| 09.05.2021 17:00 | Doljevac | 6 : 0 | Moravac (Č) |
| 09.05.2021 17:00 | Ibar | 3 : 1 | Kraljevo Hajduk | |
| 09.05.2021 17:00 | Gruža | 1 : 4 | Napredak | |
| 09.05.2021 17:00 | Budućnost | 1 : 2 | Tavnik | |
| 09.05.2021 17:00 | Jovo Kursula | 1 : 2 | Mataruge | |
| 09.05.2021 17:00 | Granit | 1 : 1 | Mladi radnik 1925 |
| 09.05.2021 17:00 | Kolare | 1 : 3 | Juhor (G) | |
| 09.05.2021 17:00 | Partizan | 2 : 1 | Morava (R) | |
| 09.05.2021 17:00 | Orlovi | 2 : 1 | Budućnost (M) | |
| 09.05.2021 17:00 | Napredak | 3 : 0 | Budućnost (Đ) | |
| 09.05.2021 17:00 | OFK Juhor 2016 | 4 : 2 | Javor | |
| 09.05.2021 17:00 | Dragocvet | 1 : 2 | Rudar | |
| 09.05.2021 17:00 | Mladost (J) | 3 : 1 | Sloga |
| 09.05.2021 16:30 | Pepeljevac | 3 : 0 | Pambukovica | |
| 09.05.2021 16:30 | Tvrdojevac | 1 : 0 | Trlić | |
| 09.05.2021 16:30 | Dimitrije Tucović | 1 : 2 | OFK Brđanac | |
| 09.05.2021 16:30 | OFK Senjak | 2 : 2 | Strmovo 1968 | |
| 09.05.2021 16:30 | Kolubara 2 | 1 : 0 | Banjani | |
| 09.05.2021 16:30 | OFK Osečina | 2 : 0 | Iskra | |
| 09.05.2021 16:30 | Joks Junajted | 2 : 1 | Radnik (Ub) |
| 09.05.2021 16:30 | Vučje | 0 : 0 | Polet | |
| 09.05.2021 16:30 | Donja Lomnica | 5 : 0 | OFK Brza | |
| 09.05.2021 16:30 | Progres | 4 : 2 | Umac | |
| 09.05.2021 16:30 | Gradac | 2 : 1 | Bobište | |
| 09.05.2021 16:30 | Zloćudovo | 2 : 3 | Bratstvo | |
| 09.05.2021 16:30 | Kumarevo 65 | 4 : 1 | Jedinstvo |
| 09.05.2021 17:00 | BSK | 6 : 2 | Mladost 1959 | |
| 09.05.2021 17:00 | Mladi borac | 3 : 0 | Sloga | |
| 09.05.2021 17:00 | Železničar | 3 : 2 | Moravac | |
| 09.05.2021 17:00 | Sloboda | 0 : 6 | Plantaža | |
| 09.05.2021 17:00 | Milanovo | 3 : 1 | Real | |
| 09.05.2021 17:00 | Šumadija | 0 : 2 | OFK Morava |
| 09.05.2021 11:00 | Prvi partizan | 2 : 1 | Avijatičar Vranjani | |
| 09.05.2021 16:30 | Savinac | 3 : 0 | Čajetina | |
| 09.05.2021 16:30 | Višesava | 2 : 1 | Kotroman | |
| 09.05.2021 16:30 | Perućac | 2 : 3 | Jedinstvo | |
| 09.05.2021 12:30 | Bakionica | 2 : 2 | Sečica | |
| 09.05.2021 16:30 | Ježevica | 1 : 0 | Omladinac | |
| 09.05.2021 16:30 | Lazarica | 5 : 2 | Polet |
| 09.05.2021 16:00 | Voćar | 1 : 3 | Prilike | |
| 09.05.2021 16:00 | Ozremica | 2 : 6 | Ovčar | |
| 09.05.2021 16:00 | Spartak | 0 : 1 | Rakova | |
| 09.05.2021 16:00 | Morava | 1 : 6 | Slatina | |
| 09.05.2021 16:00 | Dragačevo | 0 : 4 | Jedinstvo |
| 09.05.2021 16:00 | Jedinstvo (GG) | 1 : 1 | Mladost (P) | |
| 09.05.2021 16:00 | Rudar | 6 : 1 | Napredak | |
| 09.05.2021 13:00 | Orlovac | 3 : 4 | Zadrugar | |
| 09.05.2021 16:00 | Backovac Junajted | 4 : 3 | Ozrem PMH | |
| 09.05.2021 16:00 | Jedinstvo (K) | 4 : 1 | Donja Vrbava |
| 09.05.2021 16:30 | Željuša | 2 : 1 | Spartak | |
| 09.05.2021 16:30 | Gnjilan | 3 : 3 | Pobeda | |
| 09.05.2021 16:30 | Mladost | 2 : 3 | Napredak | |
| 09.05.2021 16:30 | Dragoš | 5 : 1 | Sloga |
| 09.05.2021 17:00 | Jedinstvo | 1 : 0 | Karađorđe | |
| 09.05.2021 17:00 | Hajduk Stanko | 0 : 2 | Vidojevica | |
| 09.05.2021 17:00 | Rudar | 0 : 1 | Cer (JL) | |
| 09.05.2021 17:00 | Mladost | 2 : 0 | Mladi borac | |
| 09.05.2021 17:00 | Milan Orlić | 4 : 3 | Sloga (LŠ) | |
| 09.05.2021 17:00 | Drina | 4 : 0 | Sinđelić | |
| 09.05.2021 17:00 | Duško | 2 : 1 | Majur |
| 09.05.2021 16:30 | Mladost (B) | 2 : 7 | Trnovac | |
| 09.05.2021 16:30 | Čelik | 6 : 2 | Vihor | |
| 09.05.2021 16:30 | Mineralac | 3 : 1 | FSU Južna pruga |
| 09.05.2021 16:30 | OFK Dif | 0 : 5 | Ibar |
| 09.05.2021 17:00 | Omladinac (U) | 2 : 0 | Velika Drenova | |
| 09.05.2021 17:00 | 14. Oktobar | 3 : 1 | Kamenorezac 76 | |
| 09.05.2021 17:00 | Polet 57 | 6 : 0 | Beli Orlovi | |
| 09.05.2021 17:00 | Vinogradar | 4 : 0 | Gradac | |
| 09.05.2021 17:00 | Borac | 0 : 3 | Rubin |
| 09.05.2021 17:00 | Graničar | 4 : 1 | Polet | |
| 09.05.2021 17:00 | Ratar | 0 : 0 | Ševac | |
| 09.05.2021 17:00 | Banat (D) | 3 : 1 | Karaš (K) | |
| 09.05.2021 17:00 | Dunav | 2 : 1 | Partizan (K) | |
| 09.05.2021 17:00 | Omladinac | 1 : 3 | Vulturul | |
| 09.05.2021 17:00 | Borac (VG) | 1 : 2 | Karaš (J) |
| 09.05.2021 17:00 | Dolovo | 8 : 1 | Borac (P) | |
| 09.05.2021 17:00 | Budućnost (BB) | 2 : 1 | Mladost (V) | |
| 09.05.2021 17:00 | Kolonija | 1 : 6 | Proleter | |
| 09.05.2021 17:00 | Jedinstvo (D) | 3 : 2 | Omladinac (D) |
| 09.05.2021 17:00 | ČSK | 5 : 0 | Hrtkovci | |
| 09.05.2021 17:00 | Šumar | 1 : 0 | Radnički | |
| 09.05.2021 17:00 | Graničar | 3 : 0 | Dunav | |
| 09.05.2021 17:00 | Srem | 1 : 2 | Mladost | |
| 09.05.2021 17:00 | Jedinstvo | 0 : 0 | Sremac | |
| 09.05.2021 17:00 | Krušedol | 7 : 2 | Kameni | |
| 09.05.2021 17:00 | Polet | 0 : 1 | OFK Brestač | |
| 09.05.2021 17:00 | Fruškogorac | 1 : 1 | Napredak |
| 09.05.2021 17:00 | Graničar 1924 | 4 : 0 | Trgovački | |
| 09.05.2021 17:00 | Sloboda | 1 : 4 | Fruška Gora | |
| 09.05.2021 17:00 | Sloga | 0 : 0 | Graničar (K) | |
| 09.05.2021 17:00 | Obilić 1993 | 4 : 1 | Sremac (J) | |
| 09.05.2021 17:00 | OFK Bikić | 1 : 0 | Sremac (B) | |
| 09.05.2021 17:00 | Erdevik 2017 | 0 : 1 | Fruškogorac | |
| 09.05.2021 17:00 | Jednota | 0 : 4 | Zmaj | |
| 09.05.2021 17:00 | Jedinstvo | 2 : 0 | OFK Zeka Buljubaša |
| 09.05.2021 17:00 | ŽFK Banat Bagljaš | 4 : 1 | Tisa 1933 | |
| 09.05.2021 17:00 | Zlatica | 0 : 7 | Zadrugar | |
| 09.05.2021 17:00 | OFK Stajićevo | 0 : 3 | OFK Gradnulica | |
| 09.05.2021 17:00 | Mladost | 3 : 0 | Bilećanin |
| 09.05.2021 11:00 | B 2000 | 1 : 3 | Mladost (R) | |
| 09.05.2021 16:30 | Borac | 1 : 2 | Gorski Car | |
| 09.05.2021 16:30 | Šamot | 5 : 1 | Budućnost | |
| 09.05.2021 11:00 | Trešnjevica | 3 : 2 | Mladost (J) | |
| 09.05.2021 16:30 | Kopljari | 5 : 0 | Radoje Domanović | |
| 09.05.2021 16:30 | Mladi rudar | 3 : 0 | Venčani |
| 09.05.2021 16:30 | Jedinstvo (O) | 2 : 2 | Mladi radnik (D) | |
| 09.05.2021 16:30 | Napredak (MK) | 3 : 3 | Šumadija (S) | |
| 09.05.2021 16:30 | Kruševica 1980 | 3 : 2 | Karađorđe (V) | |
| 09.05.2021 16:30 | Sloga (Z) | 0 : 0 | Feniks | |
| 09.05.2021 16:30 | Mladost (R) | 1 : 1 | BSK |
| 09.05.2021 17:00 | Omladinac | 3 : 0 | Dunav | |
| 09.05.2021 17:00 | Terekveš | 6 : 1 | Dinamo 1923 | |
| 09.05.2021 17:00 | Lipar | 4 : 0 | Jedinstvo | |
| 09.05.2021 17:00 | Bratstvo 2019 | 11 : 0 | Mladost | |
| 09.05.2021 17:00 | Polet | 9 : 1 | Kula | |
| 09.05.2021 17:00 | OFK Odžaci | 1 : 0 | Aleksa Šantić |
| 09.05.2021 17:30 | Obilić | 2 : 0 | Sloga | |
| 09.05.2021 17:30 | Čenej | 0 : 3 | Proleter | |
| 09.05.2021 17:30 | Hajduk (G) | 2 : 1 | Borac (R) | |
| 09.05.2021 17:30 | Vinogradar | 1 : 2 | Dinamo |
| 09.05.2021 16:30 | Divostin | 3 : 1 | Dobrača | |
| 09.05.2021 16:30 | Ćava | 0 : 3 | Seljak | |
| 09.05.2021 16:30 | Košutnjak | 8 : 1 | Jadran |
| 09.05.2021 16:30 | Napredak (P) | 0 : 4 | Žitkovica | |
| 09.05.2021 16:30 | Barič | 1 : 0 | Batovac | |
| 09.05.2021 16:30 | BSK 1931 | 1 : 3 | Dizel | |
| 09.05.2021 16:30 | Stig 1955 | 5 : 0 | Pek | |
| 09.05.2021 16:30 | Mladi Borac | 5 : 0 | Baštovan 2015 | |
| 09.05.2021 16:30 | Napredak (B) | 4 : 3 | Ljubičevo | |
| 09.05.2021 16:30 | Mlava (B) | 3 : 1 | Borac 2016 | |
| 09.05.2021 16:30 | Sloga (M) | 2 : 1 | Polet (V) |
| 09.05.2021 16:30 | Velika Moštanica | 1 : 0 | Rekreativo 011 | |
| 09.05.2021 16:30 | BUSK | 2 : 3 | Busije | |
| 09.05.2021 10:00 | Železnik 1930 | 0 : 6 | Šećeranac Ada |
| 09.05.2021 16:30 | Lepušnica | 2 : 1 | Avala 1939 | |
| 09.05.2021 13:00 | Pionir | 3 : 0 | Boka Seniors | |
| 09.05.2021 16:30 | Palilulac | 2 : 2 | Siti Sport Klub | |
| 09.05.2021 16:30 | Minel | 4 : 1 | Mladi proleter | |
| 09.05.2021 16:30 | OFK Crvenka | 6 : 1 | Sveti Stefan | |
| 09.05.2021 16:30 | Resnik | 1 : 0 | Pinosava |
| 09.05.2021 16:30 | OFK Boždarevac | 2 : 1 | Rušanj | |
| 09.05.2021 16:30 | Veliki Borak | 4 : 2 | Beljina |
| 09.05.2021 17:00 | Braća Vuković | 2 : 1 | Mladost 1925 | |
| 09.05.2021 17:00 | Borac (A) | 0 : 2 | Zvezda | |
| 09.05.2021 11:00 | Miločajac | 1 : 0 | Lazac | |
| 09.05.2021 17:00 | Mineral 2015 | 0 : 0 | Stubal | |
| 09.05.2021 17:00 | Jedinstvo (D) | 4 : 1 | Bogutovačka Banja | |
| 09.05.2021 17:00 | Sloga Obrva | 3 : 2 | Mladost 1981 |
| 09.05.2021 16:30 | Pobeda 1953 | 3 : 0 | Zadrugar 1947 | |
| 09.05.2021 16:30 | Zabrđe 1936 | 1 : 1 | Jasenovac | |
| 09.05.2021 16:30 | Sloga 1952 | 3 : 2 | Borac (V) | |
| 09.05.2021 16:30 | Radnički (K) | 0 : 2 | Sloga 1945 |
| 09.05.2021 17:00 | Rudar (P) | 3 : 0 | Napredak (Sv) | |
| 09.05.2021 17:00 | Napredak (St) | 4 : 2 | Radnički | |
| 09.05.2021 17:00 | Jasenovo | 1 : 5 | Sinđelić | |
| 09.05.2021 17:00 | 15. Avgust 1950 | 8 : 0 | Mladost (S) |
| 09.05.2021 17:00 | Crni Vrh | 0 : 3 | Zenit | |
| 09.05.2021 17:00 | Osaonica | 5 : 3 | Šantarovac | |
| 09.05.2021 17:00 | Jedinstvo | 0 : 1 | Vinorača | |
| 09.05.2021 17:00 | Mladost (T) | 1 : 0 | Bratstvo | |
| 09.05.2021 17:00 | Mladi Borac | 1 : 0 | Kupinovac |
| 09.05.2021 17:00 | Sloga | 4 : 1 | Ljubinić | |
| 09.05.2021 17:00 | Munja | 1 : 1 | Krtinska | |
| 09.05.2021 17:00 | OFK Urovci | 0 : 1 | Pobednik | |
| 09.05.2021 17:00 | Borac | 4 : 0 | Rvati | |
| 09.05.2021 17:00 | Partizan | 3 : 0 | Belo Polje | |
| 09.05.2021 17:00 | Skela | 1 : 0 | Proleter |
| 09.05.2021 16:30 | Kolubara (J) | 3 : 2 | Šarbane | |
| 09.05.2021 16:30 | OFK Stublenica | 3 : 4 | Polet (T) | |
| 09.05.2021 11:00 | Proleter (B) | 2 : 1 | Polet (DL) | |
| 09.05.2021 11:00 | Omladinac (K) | 1 : 2 | Joševa | |
| 09.05.2021 16:30 | Ratkovac | 4 : 2 | Crvena Jabuka | |
| 09.05.2021 16:30 | Mladost (V) | 1 : 1 | Kalenić | |
| 09.05.2021 16:30 | OFK Paljuvi | 3 : 1 | Rudar 1945 | |
| 09.05.2021 16:30 | Zvizdar 2012 | 2 : 1 | Čučuge |
| 09.05.2021 17:00 | Napredak (BT) | 3 : 3 | Terekves | |
| 09.05.2021 17:00 | Roham | 4 : 0 | Proleter | |
| 09.05.2021 17:00 | Napredak (Č) | 2 : 2 | Omladinac |
| 09.05.2021 11:00 | Stari drugari | 3 : 0 | Polet | |
| 09.05.2021 11:00 | Rakac Stave | 4 : 2 | Milenko Pavlović | |
| 09.05.2021 11:00 | Jadar 2013 | 2 : 0 | Popadić | |
| 09.05.2021 11:00 | Komanice | 1 : 0 | Rajac | |
| 09.05.2021 11:00 | Dračić 2018 | 1 : 3 | Žabari | |
| 09.05.2021 11:00 | Toplica | 2 : 0 | Junior Novo Naselje | |
| 09.05.2021 11:00 | Lukavac | 1 : 0 | Mladost (L) | |
| 09.05.2021 11:00 | Mali korak | 0 : 4 | Tešnjar |
| 09.05.2021 11:00 | Lemind 1953 | 1 : 2 | Todorovce | |
| 09.05.2021 17:00 | Mladost (B) | 3 : 0 | Navalin | |
| 09.05.2021 17:00 | Badince | 2 : 1 | Radnički | |
| 09.05.2021 17:00 | Veliko Trnjane | 4 : 0 | Sušica 2012 | |
| 09.05.2021 17:00 | MB | 3 : 1 | Mladost (DL) |
| 09.05.2021 17:00 | Jasenovik 2018 | 1 : 1 | Mezgraja | |
| 09.05.2021 17:00 | Spartak | 3 : 0 | Rujnik | |
| 09.05.2021 17:00 | Supovac | 0 : 11 | Proleter |
| 09.05.2021 17:00 | Jedinstvo | 1 : 6 | Polet (V) | |
| 09.05.2021 11:00 | Vukašinovac | 1 : 0 | Napredak 2012 | |
| 09.05.2021 11:00 | Rutevac | 3 : 5 | Borac |
| 09.05.2021 17:00 | Graničar | 3 : 2 | Jadran | |
| 09.05.2021 17:00 | Hajduk | 1 : 5 | Horgoš 1911 | |
| 09.05.2021 17:00 | Slavija | 0 : 1 | Šampion | |
| 09.05.2021 17:00 | Čoka | 1 : 1 | Tisa | |
| 09.05.2021 17:00 | Tromedja | 1 : 4 | Bačka |
| 09.05.2021 16:30 | Jezava | 2 : 3 | Omladinac |
| 09.05.2021 11:00 | Mladost 2013 | 2 : 0 | Mladost (Z) | |
| 09.05.2021 11:00 | Belpos | 2 : 1 | Sparta | |
| 09.05.2021 17:00 | Skupljen 2013 | 2 : 2 | Bobovik | |
| 09.05.2021 11:00 | Polet | 0 : 3 | Jedinstvo 2014 | |
| 09.05.2021 17:00 | Torpedo | 1 : 6 | Verko | |
| 09.05.2021 17:00 | Sloga 1949 | 2 : 1 | Hajduk |
| 09.05.2021 17:00 | Tempo | 3 : 2 | Pobeda | |
| 09.05.2021 17:00 | Glogonj | 3 : 0 | Omladinac 1927 | |
| 09.05.2021 17:00 | Unirea | 5 : 3 | Mundial |
| 09.05.2021 16:00 | Prijatelji | 9 : 0 | Gladijator | |
| 09.05.2021 16:00 | Kej | 4 : 0 | Gavrilo Princip | |
| 09.05.2021 16:00 | Vujan | 3 : 0 | Planinac | |
| 09.05.2021 16:00 | Lugovi | 3 : 2 | OFK Remont 1959 | |
| 09.05.2021 16:00 | Budućnost | 3 : 0 | Čačak 94 | |
| 09.05.2021 16:00 | Malba | 0 : 3 | Mršinci |
| 09.05.2021 17:30 | Elektrovojvodina | 1 : 1 | Vinogradar | |
| 09.05.2021 17:30 | Bikovo | 2 : 1 | Solid | |
| 09.05.2021 17:30 | Palić | 0 : 1 | Čantavir | |
| 09.05.2021 17:30 | Hajduk 1950 | 4 : 1 | Žednik | |
| 09.05.2021 17:30 | Udarnik Višnjevac | 6 : 1 | OFK Mala Bosna 2015 |
| 09.05.2021 17:30 | Orlovi (BP) | 0 : 0 | Soko | |
| 09.05.2021 17:30 | Bačka (D) | 1 : 2 | Bačka 1945 | |
| 09.05.2021 17:30 | Krivanj | 5 : 3 | Neštin | |
| 09.05.2021 17:30 | Bački Hajduk | 6 : 0 | Proleter | |
| 09.05.2021 17:30 | Borac (V) | 3 : 2 | Slavija | |
| 09.05.2021 17:30 | Mladost (MB) | 2 : 5 | Naša Zvezda |
| 09.05.2021 17:00 | OFK Jelen | 1 : 2 | OFK Letnjikovac 1983 | |
| 09.05.2021 17:00 | Pričinović | 2 : 0 | Rankovac | |
| 09.05.2021 17:00 | PSK | 3 : 2 | Vlašić | |
| 09.05.2021 17:00 | Šipurske livade | 6 : 1 | Dobrava | |
| 09.05.2021 17:00 | Petrovac 74 | 5 : 4 | Mrovska |
| 09.05.2021 | Takovski Ustanak | 3 : 1 | Majdan | |
| 09.05.2021 | Omladinac | 0 : 6 | Šumadija | |
| 09.05.2021 | Jablanica | 0 : 2 | Velereč 94 | |
| 09.05.2021 | Semedraž | 4 : 2 | Šilopaj | |
| 09.05.2021 | Brezak | 5 : 0 | FC Stella Rossa |
| 09.05.2021 17:00 | Prva Iskra | 4 : 1 | Jedinstvo (MZ) | |
| 09.05.2021 17:00 | Jadar 1961 | 3 : 2 | Sloga | |
| 09.05.2021 17:00 | Jelav | 5 : 2 | Borac | |
| 09.05.2021 17:00 | 7. Juli | 2 : 1 | Antimon | |
| 09.05.2021 17:00 | Mladost | 3 : 1 | TE Gučevo |
| 09.05.2021 17:00 | Egeta | 2 : 1 | Rtkovo | |
| 09.05.2021 17:00 | Mala Vrbica | 7 : 3 | Pontes | |
| 09.05.2021 17:00 | Omladinac | 2 : 1 | Lokomotiva | |
| 09.05.2021 17:00 | Koča Anđelković | : | Kladušnica |
| 09.05.2021 11:00 | Bjelica | 3 : 0 | Vrelo | |
| 09.05.2021 16:30 | Brezova | 7 : 0 | Jelica | |
| 09.05.2021 16:30 | Gorušica | 5 : 1 | Bratstvo | |
| 09.05.2021 16:30 | Gradina | 0 : 0 | Sloga |
| 09.05.2021 17:00 | Mladost | 1 : 0 | Gorki | |
| 09.05.2021 17:00 | Zadrugar Milkivit | 1 : 2 | Sloboda | |
| 09.05.2021 17:00 | Petlovača | 3 : 5 | Milicionar | |
| 09.05.2021 17:00 | Napredak | 8 : 2 | Partizan | |
| 09.05.2021 17:00 | Lipolist | 4 : 0 | Budućnost (ZM) | |
| 09.05.2021 17:00 | Omladinac 2013 (SL) | 1 : 1 | Budućnost (DO) | |
| 09.05.2021 17:00 | Omladinac (BO) | 1 : 2 | Torpedo 1924 |
| 09.05.2021 14:00 | Glumač | 2 : 3 | Gorobilje | |
| 09.05.2021 14:00 | Dobrinjac | 2 : 0 | Napredak | |
| 09.05.2021 17:00 | Knjaz | 2 : 0 | Duškovci | |
| 09.05.2021 17:00 | Trešnjica | 3 : 5 | Plavi Tok |
| 09.05.2021 17:00 | Mladost Radost | 4 : 0 | Jedinstvo | |
| 09.05.2021 17:00 | Tomislavci | 6 : 1 | Sloboda | |
| 09.05.2021 17:00 | Slavija | 1 : 0 | Pobeda |
| 09.05.2021 16:30 | Šumadija | 0 : 0 | Bukovac | |
| 09.05.2021 16:30 | Udarnik | 1 : 1 | Beli Orlovi |
| 09.05.2021 16:30 | Karadjordje | 1 : 4 | Jedinstvo | |
| 09.05.2021 16:30 | Omladinac | 1 : 1 | Mladost |
| 09.05.2021 11:00 | Jugovići 1976 | 2 : 5 | Rad 1974 | |
| 09.05.2021 11:00 | Lepaja 2018 | 5 : 2 | Balajnac |
| 09.05.2021 17:00 | OFK Sikole | 3 : 2 | OFK Tamnič | |
| 09.05.2021 11:00 | Miloševo | 6 : 0 | Rečka |
| 09.05.2021 11:00 | Modrica | 2 : 2 | Naupare | |
| 09.05.2021 17:00 | Mudrakovac | 1 : 4 | Parunovac | |
| 09.05.2021 11:00 | Bukovica | 0 : 4 | Pepeljevac 1947 | |
| 09.05.2021 11:00 | Polet | 0 : 1 | Gaglovo |
| 09.05.2021 11:00 | Zaplanjac | 0 : 3 | Marina Kutina | |
| 09.05.2021 11:00 | Knežica | 4 : 3 | Grkinja |
| 09.05.2021 16:30 | Podunavac | 6 : 0 | Hajduk | |
| 09.05.2021 16:30 | OFK Mladost | 2 : 3 | Umčari |
| 09.05.2021 17:00 | Palilulac | 3 : 2 | Mladost |
| 09.05.2021 13:00 | Sloboda 2013 | 3 : 0 | Sloga |
| 09.05.2021 17:00 | Mladi radnik | 6 : 3 | Parcane | |
| 09.05.2021 14:30 | Velika Morava | 1 : 4 | Varvarin | |
| 09.05.2021 14:30 | Stara Čaršija | 2 : 0 | Obilić | |
| 09.05.2021 14:30 | Ratajac | 5 : 1 | Mladost |
| 09.05.2021 17:00 | KSK Konak 1926 | 0 : 16 | Sloga | |
| 09.05.2021 17:00 | Proleter | 0 : 4 | Borac |
| 09.05.2021 17:00 | Magnohrom | 4 : 2 | Partizan | |
| 09.05.2021 11:00 | Biljanovac | 0 : 2 | Studen Vitez | |
| 09.05.2021 16:00 | BSK 2014 | 4 : 4 | Koštam Polje | |
| 09.05.2021 11:00 | Stara Čaršija | 0 : 0 | Zgodačica | |
| 09.05.2021 17:00 | Šumadija | 2 : 1 | Morava |
| 09.05.2021 16:30 | Planinac | 2 : 1 | Borac (S) | |
| 09.05.2021 16:30 | Sloga (S) | 2 : 3 | Graničar | |
| 09.05.2021 16:30 | Jedinstvo (K) | 7 : 4 | Fruškogorac | |
| 09.05.2021 16:30 | Car Uroš | 1 : 1 | Borac (J) | |
| 09.05.2021 16:30 | Polet | 3 : 1 | Donji Petrovci | |
| 09.05.2021 16:30 | 27. Oktobar | 2 : 4 | Vojvodina |
| 09.05.2021 11:00 | OFK Takovo | 2 : 2 | Jedinstvo (M) | |
| 09.05.2021 11:00 | Vukona | 0 : 3 | Gunjevac | |
| 09.05.2021 11:00 | Sloga (V) | 0 : 3 | Sovljak | |
| 09.05.2021 11:00 | Tamnava | 2 : 2 | Brgule | |
| 09.05.2021 11:00 | Budućnost 1995 | 0 : 2 | Kolubara (LP) | |
| 09.05.2021 11:00 | Murgaš 2012 | 1 : 0 | Dokmir |
| 09.05.2021 17:00 | Mladost | 3 : 4 | Donja Mutnica | |
| 09.05.2021 17:00 | Polet | 0 : 1 | Borac 1950 | |
| 09.05.2021 17:00 | Železničar | 1 : 3 | Omladinac | |
| 09.05.2021 10:00 | BSK Buljane | 3 : 0 | Popovac |
| 09.05.2021 17:00 | Razvitak | 5 : 2 | Jedinstvo | |
| 09.05.2021 17:00 | Moravac | 2 : 1 | Potočac |
| 09.05.2021 17:00 | Graničar (R) | 5 : 0 | Sport | |
| 09.05.2021 17:00 | Jedinstvo Lemeš | 2 : 5 | Telečka |
| 09.05.2021 17:30 | Oniks | 1 : 4 | Belica | |
| 09.05.2021 17:30 | Dražmirovac | 0 : 3 | GFK Strelište | |
| 09.05.2021 17:30 | Mladi radnik | 2 : 3 | Omladinac | |
| 09.05.2021 17:30 | OFK Dragoševac | 6 : 1 | Napredak |
| 09.05.2021 11:00 | Stig (MC) | 1 : 5 | Šapine | |
| 09.05.2021 11:00 | BSK 1924 | 2 : 3 | Radnik (S) |
| 09.05.2021 17:00 | Rapid | 1 : 4 | Sloga | |
| 09.05.2021 17:00 | Janošik | 2 : 2 | Mladost (VG) | |
| 09.05.2021 17:00 | Dobrica | 1 : 1 | Vladimirovac |
| 09.05.2021 17:00 | Hajduk | 4 : 4 | Vitorul | |
| 09.05.2021 17:00 | Vinogradar | 2 : 1 | Pobeda |
| 09.05.2021 11:00 | Junkovac | 2 : 5 | Šumadinac 1949 | |
| 09.05.2021 11:00 | Kalipolje | 5 : 2 | Maskar | |
| 09.05.2021 11:00 | Krćevac 04 | 3 : 2 | Jarmenovci |
| 09.05.2021 10:00 | Napredak | 1 : 2 | Mladost | |
| 09.05.2021 11:00 | Radnik 2013 | 1 : 5 | Jašunja | |
| 09.05.2021 11:00 | Rudar 1973 | 5 : 2 | ŠFU Derbi 2016 |
| 09.05.2021 16:30 | Bukorovac | 3 : 1 | Jovanovac | |
| 09.05.2021 16:30 | Hajduk 1936 | 0 : 0 | Kragujevac | |
| 09.05.2021 16:30 | Stanovo 1941 | 7 : 1 | Kremenac |
| 09.05.2021 16:30 | Metalac | 2 : 2 | Sloga (D) | |
| 09.05.2021 16:30 | Pobeda | 1 : 3 | Napredak 1934 | |
| 09.05.2021 16:30 | Proleter 1932 | 2 : 4 | Beli Orao |
| 09.05.2021 16:30 | Mip Majdan | 5 : 0 | Moravac 1933 | |
| 09.05.2021 16:30 | Sloga 1932 | 5 : 2 | Margum | |
| 09.05.2021 16:30 | Morava 1932 | 3 : 1 | Dunavac | |
| 09.05.2021 16:30 | Sopot | 3 : 1 | Dunav |
| 09.05.2021 16:30 | Srem (SR) | 7 : 0 | Borac (VR) | |
| 09.05.2021 16:30 | Borac (R) | 0 : 1 | Sloga | |
| 09.05.2021 16:30 | Poletarac | 2 : 5 | OFK Bosut | |
| 09.05.2021 16:30 | Srem (SM) | 7 : 2 | Planinac |
| 09.05.2021 11:00 | Sava | 2 : 0 | Borac BTG | |
| 09.05.2021 11:00 | Mladost Svileuva | 3 : 1 | Korman | |
| 09.05.2021 11:00 | Galeb 1984 | 2 : 1 | Rudar | |
| 09.05.2021 11:00 | Miloš Pocerac | 1 : 4 | Dobrava Žabar 2020 |
| 09.05.2021 11:00 | Maovi MH | 5 : 0 | Bojić | |
| 09.05.2021 11:00 | Mladost | 0 : 2 | Metlić | |
| 09.05.2021 11:00 | Zablaće | 0 : 4 | Dumača | |
| 09.05.2021 11:00 | Pocerina | 5 : 2 | Jedinstvo |
| 09.05.2021 11:00 | POFK Letnjikovac | 0 : 8 | Culjković | |
| 09.05.2021 11:00 | Sloga | 2 : 2 | Roma - Odžino selo |
| 09.05.2021 16:30 | Budućnost | 0 : 1 | Polet |
| 09.05.2021 10:00 | Mlava (R) | 1 : 1 | Vrelo 1971 | |
| 09.05.2021 10:00 | Homoljac | 2 : 2 | Sloga (J) | |
| 09.05.2021 10:00 | Budućnost (M) | 4 : 2 | Bliznak-Medveđica | |
| 09.05.2021 10:00 | Best Sige | 1 : 2 | Vukovac 98 |
| 09.05.2021 16:30 | Proleter | 0 : 15 | Sloga | |
| 09.05.2021 16:30 | Kačer | 0 : 1 | Nepričava |
| 09.05.2021 17:00 | Sloga | 4 : 0 | Granit | |
| 09.05.2021 17:00 | Mladost (B) | 5 : 1 | Mladost (L) | |
| 09.05.2021 17:00 | Jadar | 0 : 4 | Luk Kompenzatori |
| 09.05.2021 16:30 | Radnički (P) | 2 : 0 | Sloga-Top | |
| 09.05.2021 16:30 | Ram | 3 : 0 | Stiški Kurjak |
| 09.05.2021 17:00 | Vinogradar | 13 : 0 | Resava |
| 09.05.2021 11:00 | Mladost | 1 : 4 | Stojan Lazarac | |
| 09.05.2021 11:00 | OFK Napredak 1933 | 3 : 0 | Napredak (U) | |
| 09.05.2021 11:00 | Radnik | 0 : 2 | Bair |
| 09.05.2021 17:00 | Polet | 1 : 1 | Grkljane | |
| 09.05.2021 11:00 | Padež | 2 : 1 | Vratare | |
| 09.05.2021 11:00 | Dedina | 7 : 1 | Kruševica |
| 09.05.2021 16:30 | Mladost | 1 : 3 | Polet | |
| 09.05.2021 16:30 | Žika Marković Uča | 1 : 3 | Mrčkovac |
| 09.05.2021 11:00 | Ranilović 1970 | 2 : 1 | Misača |
| 09.05.2021 16:30 | Omladinac | 9 : 0 | Jedinstvo (M) | |
| 09.05.2021 16:30 | Borac | 0 : 4 | OFK Bačinci | |
| 09.05.2021 16:30 | OFK Bingula | 1 : 0 | Jedinstvo (Lj) | |
| 09.05.2021 16:30 | Napredak | 6 : 0 | Graničar |
| 09.05.2021 17:00 | Kupinovo | 1 : 1 | Sloven | |
| 09.05.2021 17:00 | Lovac | 10 : 1 | Mladost 1935 | |
| 09.05.2021 17:00 | Vitez | 0 : 4 | Hajduk 1932 |
| 09.05.2021 17:00 | OFK Polet | 1 : 4 | Proleter | |
| 09.05.2021 17:00 | Sloga | 0 : 0 | Šumadinac | |
| 09.05.2021 17:00 | Bistrica | 3 : 3 | Vreoci | |
| 09.05.2021 17:00 | Dimitrije Tucović | 1 : 0 | Mladost |
| 09.05.2021 17:00 | Lipar | 2 : 1 | Morava |
| 09.05.2021 18:00 | Budućnost | 3 : 1 | Rudar | |
| 09.05.2021 19:00 | OFK Petrovac | 1 : 0 | Iskra | |
| 09.05.2021 18:00 | OFK Titograd | 1 : 2 | Jezero | |
| 09.05.2021 20:00 | Podgorica | 2 : 1 | Zeta | |
| 09.05.2021 19:00 | Sutjeska | 1 : 2 | Dečić |
| 09.05.2021 20:00 | Arsenal | 3 : 1 | West Bromwich Albion | |
| 09.05.2021 15:05 | Aston Villa | 1 : 3 | Manchester United | |
| 09.05.2021 17:30 | West Ham United | 0 : 1 | Everton | |
| 09.05.2021 13:00 | Wolverhampton | 2 : 1 | Brighton |
| 09.05.2021 14:00 | Getafe | 0 : 1 | Eibar | |
| 09.05.2021 21:00 | Real Madrid | 2 : 2 | Sevilla | |
| 09.05.2021 16:15 | Valencia | 3 : 0 | Real Valladolid | |
| 09.05.2021 18:30 | Villarreal | 2 : 4 | Celta Vigo |
| 09.05.2021 15:30 | Eintracht Frankfurt | 1 : 1 | Mainz 05 | |
| 09.05.2021 18:00 | Hertha BSC | 0 : 0 | Arminia | |
| 09.05.2021 13:30 | Köln | 1 : 4 | Freiburg |
| 09.05.2021 15:00 | Angers SCO | 3 : 0 | Dijon | |
| 09.05.2021 15:00 | Metz | 0 : 3 | Nîmes | |
| 09.05.2021 15:00 | Nice | 3 : 2 | Brest | |
| 09.05.2021 17:05 | Reims | 0 : 1 | Monaco | |
| 09.05.2021 21:00 | Rennes | 1 : 1 | PSG | |
| 09.05.2021 13:00 | Saint-Etienne | 1 : 0 | Olympique Marseille | |
| 09.05.2021 15:00 | Strasbourg | 2 : 3 | Montpellier |
| 09.05.2021 15:00 | Parma | 2 : 5 | Atalanta | |
| 09.05.2021 15:00 | Benevento | 1 : 3 | Cagliari | |
| 09.05.2021 18:00 | Roma | 5 : 0 | Crotone | |
| 09.05.2021 20:45 | Juventus | 0 : 3 | Milan | |
| 09.05.2021 12:30 | Genoa | 1 : 2 | Sassuolo | |
| 09.05.2021 15:00 | Hellas Verona | 1 : 1 | Torino |
| 09.05.2021 15:00 | ŽGFK Lavice Dubočica | 3 : 3 | Loznica | |
| 09.05.2021 13:00 | Majdanpek | 1 : 1 | Moskva |
| 09.05.2021 11:00 | Banat | 7 : 3 | Voja Gačić |
| 09.05.2021 13:00 | Slatke male | 0 : 5 | Karađorđe | |
| 09.05.2021 14:00 | Jedinstvo | 6 : 0 | Šabac |
| 09.05.2021 16:00 | Levač | 4 : 0 | Rudar 1974 | |
| 09.05.2021 13:00 | Kolibri | 13 : 0 | SUŽF Stol |
| 09.05.2021 17:00 | Desetka | 0 : 4 | Heroj Polet B tim |
| 09.05.2021 11:00 | Mladost (L) | 1 : 3 | Radnički (NB) | |
| 09.05.2021 13:00 | IMT | 1 : 1 | Spartak ŽK | |
| 09.05.2021 10:00 | Rad | 1 : 1 | RFK Grafičar | |
| 09.05.2021 10:00 | Voždovac | 1 : 5 | Crvena zvezda | |
| 09.05.2021 13:00 | RFK Novi Sad 1921 | 1 : 3 | Radnički 1923 | |
| 09.05.2021 11:00 | TSC | 2 : 2 | Vojvodina | |
| 09.05.2021 11:00 | Napredak | 0 : 0 | Partizan |
| 09.05.2021 11:00 | Vojvodina | 1 : 2 | Radnički 1912 | |
| 09.05.2021 10:00 | Proleter (NS) | 0 : 2 | Omladinac |
| 09.05.2021 10:00 | Bačka 1901 | 0 : 6 | Kabel |
| 09.05.2021 10:00 | Dinamo 1945 | 3 : 0 | Radnički (NP) | |
| 09.05.2021 10:00 | Jedinstvo (V) | 3 : 0 | Radnički (SM) | |
| 09.05.2021 10:00 | Index | 0 : 1 | GFK Sloven | |
| 09.05.2021 13:00 | Radnički (ZR) | 2 : 4 | Podrinje |
| 09.05.2021 16:30 | Radnički (V) | 3 : 1 | Morava (VP) | |
| 09.05.2021 13:00 | Javor Matis | 2 : 1 | Jedinstvo (Ub) | |
| 09.05.2021 16:30 | Loznica | : | Sloboda | |
| 09.05.2021 13:30 | Sloga (P) | 0 : 0 | Metalac | |
| 09.05.2021 13:30 | Borac 1926 | 2 : 1 | GFK Sloboda | |
| 09.05.2021 10:00 | BIP | 5 : 0 | Budućnost Krušik 2014 | |
| 09.05.2021 13:30 | Sloga (K) | 6 : 0 | Šumadija (A) |
| 09.05.2021 | Bor 1919 | 2 : 2 | Trstenik PPT | |
| 09.05.2021 | Real | 5 : 0 | Radnik |
| 09.05.2021 11:00 | Zvezda | 6 : 2 | Rvati |
| 09.05.2021 10:00 | OFK Žarkovo | 5 : 1 | Bežanija |
| 09.05.2021 12:00 | Jedinstvo | 2 : 0 | Budućnost | |
| 09.05.2021 10:00 | GSP Polet Dorćol | 3 : 0 | Mladenovac |
| 09.05.2021 09:00 | IMT | 0 : 1 | BSK Borča |
| 09.05.2021 10:00 | Napredak | 1 : 1 | Sopot |
| 09.05.2021 15:00 | Mladost (L) | 2 : 0 | Mačva | |
| 09.05.2021 12:30 | Rad | 4 : 1 | RFK Grafičar |