| 06.10.2021 18:00 | OFK Bačka | 0 : 0 | Mačva | |
| 06.10.2021 15:00 | Zlatibor | 0 : 5 | OFK Žarkovo | |
| 06.10.2021 15:00 | Timok 1919 | 0 : 1 | Inđija | |
| 06.10.2021 15:00 | IMT | 0 : 1 | Javor Matis | |
| 06.10.2021 15:00 | Mladost GAT | 1 : 0 | Rad | |
| 06.10.2021 15:00 | Budućnost | 2 : 1 | Loznica | |
| 06.10.2021 15:00 | Železničar | 2 : 0 | Kabel |
| 06.10.2021 15:00 | GFK Sloboda | 1 : 0 | Trepča |
| 06.10.2021 15:00 | Bane 1931 | 1 : 2 | Budućnost |
| 06.10.2021 15:00 | Vrelo Sport | 4 : 0 | Sloga |
| 06.10.2021 15:00 | Pomoravlje 1946 | 4 : 1 | Karađorđe |
| 06.10.2021 15:00 | Jedinstvo (GM) | 8 : 0 | Rudar | |
| 06.10.2021 15:00 | Malošište | 2 : 3 | Mladost (B) | |
| 06.10.2021 15:00 | Orljane | 8 : 1 | Aluminjum | |
| 06.10.2021 15:00 | Naša krila 1936 | 1 : 1 | Bukovik | |
| 06.10.2021 15:00 | Morava | 0 : 4 | OFK Sinđelić | |
| 06.10.2021 15:00 | Pukovac | 2 : 0 | OFK Napredak 1929 | |
| 06.10.2021 15:00 | OFK Niš | 0 : 1 | Delijski Vis | |
| 06.10.2021 15:00 | Car Konstantin | 1 : 0 | Mladost (M) |
| 06.10.2021 15:00 | Čekmin | 1 : 0 | Moravac Orion | |
| 06.10.2021 15:00 | Plantaža | 1 : 1 | Svetlost | |
| 06.10.2021 15:00 | Jablanica | 5 : 4 | Žitorađa | |
| 06.10.2021 15:00 | Radan | 1 : 2 | OFK Topličanin | |
| 06.10.2021 15:00 | Vranjska Banja | 1 : 1 | OFK Alakince | |
| 06.10.2021 15:00 | Nebeski Andjeli | 2 : 2 | Jedinstvo | |
| 06.10.2021 15:00 | Trnovac | 0 : 0 | SFK Morava |
| 06.10.2021 15:00 | Župa | 7 : 0 | Levač | |
| 06.10.2021 15:00 | OFK Lugomir | 0 : 2 | Jedinstvo 1936 | |
| 06.10.2021 15:00 | Trstenik PPT | 2 : 0 | Jedinstvo (M) | |
| 06.10.2021 15:00 | Sloga (D) | 1 : 3 | Sloga (M) | |
| 06.10.2021 15:00 | Orlovi | 5 : 2 | Blagotin | |
| 06.10.2021 15:00 | Juhor | 1 : 9 | SFS Borac | |
| 06.10.2021 15:00 | Kušiljevo | 1 : 2 | Morava 1918 |
| 06.10.2021 15:00 | Jedinstvo (P) | 1 : 1 | Brodoremont | |
| 06.10.2021 15:00 | BSK | 5 : 1 | Sloga | |
| 06.10.2021 15:00 | Bor 1919 | 0 : 1 | OFK Slatina | |
| 06.10.2021 15:00 | Balkanski | 1 : 0 | Lužnica | |
| 06.10.2021 15:00 | Ozren | 1 : 2 | Tanasko Rajić | |
| 06.10.2021 15:00 | Dunav | 5 : 0 | OFK 019 | |
| 06.10.2021 15:00 | Rajko Mitić | 3 : 1 | OFK Knjaz | |
| 06.10.2021 15:00 | Đerdap | 7 : 0 | Zvezda |
| 06.10.2021 15:30 | Turbina | 0 : 0 | Krtinska |
| 06.10.2021 15:30 | Milenko Pavlović | 5 : 3 | Polet |
| 06.10.2021 15:30 | Spartak DOO | 2 : 2 | Zemun |
| 06.10.2021 12:00 | Spartak ŽK | 3 : 3 | RFK NS 1921 |
| 06.10.2021 12:00 | Mačva 1929 | 3 : 1 | Rađevac | |
| 06.10.2021 11:00 | Budućnost Krušik 2014 | 3 : 1 | Vrelo Sport |
| 06.10.2021 15:00 | Loznica | 0 : 0 | Železničar |
| 06.10.2021 20:00 | TSC '09 | 0 : 1 | TSC '10 |
| 06.10.2021 16:30 | Vojvodina 021 | 58 : 81 | Budućnost |
| 06.10.2021 18:00 | Badel 1862 | 59 : 92 | Cinkarna Celje | |
| 06.10.2021 18:00 | Montana 2003 | 100 : 45 | RMU Banovići |
| 06.10.2021 17:30 | Jedinstvo | 46 : 77 | Vizura |
| 06.10.2021 17:00 | Mokra Gora | 27 : 36 | Šamot 65 |
| 06.10.2021 20:30 | Nova Pazova 1957 | 39 : 29 | Radnički |
| 06.10.2021 20:00 | Sivac 69 - 2 | 33 : 24 | Kljajićevo |
| 06.10.2021 19:30 | Bor - RTB 2 | : | Hajduk Veljko |
| 06.10.2021 21:00 | Zemun | 8 : 20 | KVK Radnički | |
| 06.10.2021 19:00 | Novi Beograd | 32 : 1 | Nais | |
| 06.10.2021 20:00 | BVK Crvena zvezda | 11 : 9 | Vojvodina | |
| 06.10.2021 21:00 | Valis | 10 : 9 | Proleter |
Učitavanje...
