| Kolo | Datum/Vreme | Utakmica | Rezultat |
|---|---|---|---|
| 1 | 20.10.2021 18:00 | Žitorađa - Radan | 19:23 |
| 2 | 11.12.2021 13:00 | Radan - Aleksinac | 25:19 |
| 3 | 16.10.2021 13:30 | Vranje - Radan | 23:17 |
| 4 | 24.10.2021 13:00 | Radan - Osice | 20:28 |
| 5 | 30.10.2021 15:00 | Mladost - Radan | 31:19 |
| 7 | 14.11.2021 13:00 | Radan - Remesiana | 21:29 |
| 8 | 19.11.2021 20:00 | Vlasotince - Radan | 25:14 |
| 9 | 28.11.2021 13:00 | Radan - RSU Feniks | 21:21 |
| 10 | 02.04.2022 18:00 | Radan - Žitorađa | 16:25 |
| 11 | 12.03.2022 12:00 | Aleksinac - Radan | 42:12 |
| 12 | 20.03.2022 13:00 | Radan - Vranje | 17:40 |
| 13 | 26.03.2022 20:30 | Osice - Radan | 36:20 |
| 14 | 03.04.2022 13:00 | Radan - Mladost | 26:26 |
| 16 | 17.04.2022 18:00 | Remesiana - Radan | 30:19 |
| 17 | 30.04.2022 13:00 | Radan - Vlasotince | 17:32 |
| 18 | 08.05.2022 17:30 | RSU Feniks - Radan | 35:22 |
| Poz | Tim | Utak | Pob | Ner | Por | DG | PG | GR | Forma | Bod | |
| 1 | Vlasotince | 16 | 14 | 0 | 2 | 470 | 338 | +132 | 1 2 1 1 1 | 28 | |
| 2 | Osice | 16 | 12 | 2 | 2 | 557 | 424 | +133 | 2 1 1 1 1 | 26 | |
| 3 | Remesiana | 16 | 13 | 0 | 3 | 437 | 346 | +91 | 1 1 2 1 2 | 26 | |
| 4 | Vranje | 16 | 7 | 4 | 5 | 373 | 341 | +32 | 2 2 1 X 1 | 18 | |
| 5 | RSU Feniks | 16 | 7 | 1 | 8 | 400 | 399 | +1 | 1 2 2 1 1 | 15 | |
| 6 | Mladost | 16 | 6 | 1 | 9 | 442 | 485 | -43 | X 1 2 2 2 | 13 | |
| 7 | Aleksinac | 16 | 3 | 1 | 12 | 359 | 448 | -89 | 2 2 1 2 2 | 7 | |
| 8 | Radan | 16 | 2 | 2 | 12 | 309 | 461 | -152 | 2 X 2 2 2 | 6 | |
| 9 | Žitorađa | 16 | 2 | 1 | 13 | 365 | 470 | -105 | 2 2 X 2 1 | 5 | |
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